Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28917465 | 0.83 | HIF1A (0.46) | HIF1ANPBWR1MCHR1XDHATM | |
| SCHEMBL29955120 | 0.83 | NPC1 (0.51) | NPBWR1MCHR1MAPTRAB9AL3MBTL1 | |
| SCHEMBL15330970 | 0.83 | ALDH1A1 (0.41) | NPBWR1MCHR1L3MBTL1KDM4EMEN1 | |
| SCHEMBL15332330 | 0.82 | NPC1 (0.44) | NPBWR1MCHR1MAPTRAB9AKDM4E | |
| SCHEMBL29951366 | 0.82 | HIF1A (0.45) | HIF1ANPBWR1MCHR1XDHATM | |
| SCHEMBL15331047 | 0.80 | NPC1 (0.42) | NPBWR1MCHR1MAPTRAB9AKDM4E | |
| SCHEMBL3321144 | 0.79 | RAB9A (0.49) | HIF1ANPBWR1MAPTRAB9AMEN1 | |
| SCHEMBL10561539 | 0.78 | GABRB3 (0.43) | — | |
| SCHEMBL19120598 | 0.76 | NPBWR1 (0.49) | HIF1ANPBWR1MCHR1XDHBRAF | |
| SCHEMBL19120335 | 0.76 | HIF1A (0.44) | HIF1ANPBWR1MCHR1XDHBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |