SCHEMBL29951003

SCHEMBL29951003

Cc1cccc(-c2ccccc2B(O)O)c1C

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.41
ATM Q13315 1/20 0.41
P2RX7 Q99572 1/20 0.38
ENPP2 Q13822 1/20 0.38
MYC P01106 1/20 0.36
TSHR P16473 1/20 0.36
ACHE P22303 1/20 0.36
NUDT1 P36639 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CNR2 P34972 2/20 0.34
CNR1 P21554 1/20 0.34
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
CHEK1 O14757 1/20 0.33
WEE1 P30291 1/20 0.33
SLC9A1 P19634 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29957084 0.85 ENPP2 (0.41) ENPP2TSHRACHE
SCHEMBL969623 0.85 ENPP2 (0.41) ENPP2TSHRACHE
SCHEMBL18576541 0.83 ENPP2 (0.38) TRPA1ATMENPP2MYCTSHR
SCHEMBL910658 0.82 ENPP2 (0.50) ENPP2
SCHEMBL28704817 0.81 MYC (0.50) ENPP2MYCTSHRACHEALDH1A1
SCHEMBL309076 0.80 TRPA1 (0.50) TRPA1ATMENPP2TSHRACHE
SCHEMBL29479067 0.80 TRPA1 (0.50) TRPA1ATMENPP2TSHRACHE
SCHEMBL218508 0.79 TRPA1 (0.52) TRPA1ATMP2RX7TSHRACHE
SCHEMBL30834716 0.79 TRPA1 (0.52) TRPA1ATMP2RX7TSHRACHE
SCHEMBL28220679 0.78 TRPA1 (0.48) TRPA1ATMENPP2TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed