Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101964 | 1.00 | IDO1 (0.47) | IDO1MAPTL3MBTL1KDM4EGAA | |
| SCHEMBL6243496 | 0.82 | IDO1 (0.46) | IDO1MAPTL3MBTL1KDM4EGAA | |
| SCHEMBL28862765 | 0.79 | IDO1 (0.44) | IDO1MAPTL3MBTL1KDM4EGAA | |
| SCHEMBL31244592 | 0.74 | PARP1 (0.40) | MAPTL3MBTL1KDM4EGAAGSK3B | |
| SCHEMBL29955806 | 0.74 | CACNB4 (0.41) | GAA | |
| SCHEMBL29954649 | 0.74 | TP53 (0.46) | MAPTALDH1A1TP53SMN1; SMN2EGFR | |
| SCHEMBL29952427 | 0.74 | EPHX2 (0.40) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL29956773 | 0.74 | GAA (0.39) | MAPTKDM4EGAACREBBPALDH1A1 | |
| SCHEMBL29953205 | 0.74 | PGR (0.43) | IDO1MAPTTDO2MEN1TP53 | |
| SCHEMBL1314441 | 0.74 | HTR7 (0.40) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |