Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12307956 | 1.00 | KMT2A (0.46) | KMT2ADYRK1ATDP1HPGDHSD17B10 | |
| SCHEMBL29955390 | 0.86 | SRC (0.47) | KMT2ADYRK1ATDP1HPGDHSD17B10 | |
| SCHEMBL2885051 | 0.86 | SRC (0.47) | KMT2ADYRK1ATDP1HPGDHSD17B10 | |
| SCHEMBL4094352 | 0.82 | KDM4E (0.51) | KMT2ATDP1HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL15427919 | 0.81 | PDK1 (0.44) | KMT2ATDP1HPGDSRCALDH1A1 | |
| SCHEMBL20766369 | 0.81 | DYRK1A (0.48) | KMT2ADYRK1AALDH1A1CYP2C19NPC1 | |
| SCHEMBL1042827 | 0.80 | KMT2A (0.46) | KMT2AHPGDSRCALDH1A1CYP1A2 | |
| SCHEMBL22024054 | 0.80 | PDK1 (0.43) | KMT2AHPGDSRCALDH1A1CYP1A2 | |
| SCHEMBL4956208 | 0.80 | SMN1; SMN2 (0.50) | KMT2ADYRK1ATDP1HPGDHSD17B10 | |
| SCHEMBL28568397 | 0.79 | KCNMA1 (0.66) | KMT2ATDP1HPGDCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |