Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.50 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.50 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.50 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.50 |
| ▸ | CBFB | Q13951 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LDHA | P00338 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074611 | 0.88 | KDM4E (0.41) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL377917 | 0.82 | ALDH1A1 (0.54) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL1527112 | 0.82 | PKM (0.56) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL29958034 | 0.82 | ALDH1A1 (0.54) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL29951047 | 0.82 | KMT2A (0.46) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL12307956 | 0.82 | KMT2A (0.46) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL7055271 | 0.81 | MEN1 (0.50) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL5577982 | 0.81 | RORC (0.53) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL20766369 | 0.81 | DYRK1A (0.48) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL10061909 | 0.79 | ALDH1A1 (0.50) | KDM4EMEN1MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445516-B2 | Pharmaceutical composition for promoting angiogenesis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-05-21 | — | — | US | disclosed |
| US-20090187025-A1 | Pharmaceutical composition for promoting angiogenesis | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-1708705-B1 | USE OF PIPERIDINE DERIVATIVES FOR PROMOTING ANGIOGENESIS | OTSUKA PHARMA CO LTD (JP) | 2009-02-18 | — | — | EP | disclosed |
| EP-1708705-A1 | PHARMACEUTICAL COMPOSITION FOR PROMOTING ANGIOGENESIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005072734-A1 | PHARMACEUTICAL COMPOSITION FOR PROMOTING ANGIOGENESIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090187025-A1 | Pharmaceutical composition for promoting angiogenesis | FLT1, FLT4, KDR | KDM4E 837/4885MEN1 4115/4885MAPT 4708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.