Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2654910 | 0.77 | CRHBP (0.39) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL29950643 | 0.77 | ERN1 (0.34) | CCR1 | |
| SCHEMBL17558638 | 0.76 | — | — | |
| SCHEMBL18150327 | 0.74 | CCR1 (0.41) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL29706502 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL29951057 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL1584446 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL23362591 | 0.70 | ALDH1A1 (0.44) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL29957674 | 0.69 | NFE2L2 (0.40) | ALDH1A1TDP1KMT2AHPGDHSD17B10 | |
| SCHEMBL28997057 | 0.69 | NFE2L2 (0.40) | ALDH1A1TDP1KMT2AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |