Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17315652 | 0.79 | ERN1 (0.31) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL29951057 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL1584446 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL29951083 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL18150327 | 0.77 | CCR1 (0.41) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL29706502 | 0.77 | ALDH1A1 (0.35) | ALDH1A1TDP1MEN1KMT2ACCR1 | |
| SCHEMBL20268024 | 0.77 | HSD17B10 (0.34) | ALDH1A1TDP1GAACYP3A4TSHR | |
| SCHEMBL2226680 | 0.77 | CYP3A4 (0.35) | ALDH1A1MEN1KMT2AGAAGLA | |
| SCHEMBL1321340 | 0.77 | RRM2 (0.45) | ALDH1A1TDP1MEN1KMT2AGAA | |
| SCHEMBL29736642 | 0.77 | HSD17B10 (0.34) | ALDH1A1TDP1GAACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250331521-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING AN OXIME GROUP, AGRICULTURAL OR HORTICULTURAL HERBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE COMPOUND OR THE HERBICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2025-10-30 | — | — | US | disclosed |
| EP-4480950-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING OXIME GROUP, AGRICULTURAL/HORTICULTURAL HERBICIDE CONTAINING SAID COMPOUND, AND USE OF BOTH OF FOREGOING | Nihon Nohyaku Co., Ltd. (JP) | 2024-12-25 | — | — | EP | disclosed |
| CN-118891254-A | Nitrogen-containing heterocyclic compound having oxime group, agrohorticultural herbicide containing the same, and method of using the same | 日本农药株式会社 | 2024-11-01 | — | — | CN | disclosed |
| CN-117069724-A | Fused ring compounds, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| WO-2023210792-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING OXIME GROUP, AGRICULTURAL/HORTICULTURAL HERBICIDE CONTAINING SAID COMPOUND, AND USE OF BOTH OF FOREGOING | 日本農薬株式会社 | 2023-11-02 | — | — | WO | disclosed |
| WO-2023210792-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING OXIME GROUP, AGRICULTURAL/HORTICULTURAL HERBICIDE CONTAINING SAID COMPOUND, AND USE OF BOTH OF FOREGOING | 日本農薬株式会社 | 2023-11-02 | — | — | WO | disclosed |
| US-11802122-B2 | 2-oxoimidazolidine-4-carboxamides as NAv1.8 inhibitors | MERCK SHARP & DOHME LLC (US) | 2023-10-31 | — | — | US | disclosed |
| US-20230312528-A1 | 2-OXO-IMIDAZOLIDINE-4-CARBOXAMIDES AS NAV1.8 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2023-10-05 | — | — | US | disclosed |
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |
| US-20210403457-A1 | 2-OXOIMIDAZOLIDINE-4-CARBOXAMIDES AS NAV1.8 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2021-12-30 | — | — | US | disclosed |
| US-20090012082-A1 | hedgehog genes antagonists such as N-[5-(1H-benzimidazol-2-yl)-6-chloropyridin-3-yl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide, used as anticarcinogenic or antitumor agents | CURIS, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| US-20080161347-A1 | Substituted Aryl and Heteroaryl Derivatives, Compositions Containing Such Compounds and Methods of Use | MERCK & CO., INC. (US) | 2008-07-03 | — | — | US | disclosed |
| EP-1526774-B1 | SYNERGISTICALLY ACTING HERBICIDAL MIXTURES | BASF SE (DE) | 2008-05-21 | — | — | EP | disclosed |
| EP-1917857-A1 | Synergistically acting herbicidal mixtures | BASF SE (DE) | 2008-05-07 | — | — | EP | disclosed |
| EP-1863755-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES | Merck & Co., Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| EP-1807074-A1 | MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO | Curis, Inc. (US) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006102067-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES | MERCK & CO., INC. (US) | 2006-09-28 | — | — | WO | disclosed |
| WO-2006050506-A1 | MEDIATORS OF HEDGEHOG SIGNALING PATHWAYS, COMPOSITIONS AND USES RELATED THERETO | CURIS, INC. (US) | 2006-05-11 | — | — | WO | disclosed |
| EP-0254052-A1 | 2-Mono and 2,3-bis (poly) chloromethyl) pyridines | THE DOW CHEMICAL COMPANY (US) | 1988-01-27 | — | — | EP | disclosed |
| US-4713460-A | 2,3-bis-(poly)(chloromethyl)pyridines | THE DOW CHEMICAL COMPANY (US) | 1987-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403457-A1 | 2-OXOIMIDAZOLIDINE-4-CARBOXAMIDES AS NAV1.8 INHIBITORS | SCN8A, TRPV1, SCN2A | CRHBP 1856/4885CRHR2 1033/4885ALDH1A1 1922/4885 |
| US-20250331521-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING AN OXIME GROUP, AGRICULTURAL OR HORTICULTURAL HERBICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE COMPOUND OR THE HERBICIDE | DDT, HDHD5, HAAO | CRHBP 1797/4885CRHR2 1321/4885ALDH1A1 1821/4885 |
| US-20090012082-A1 | hedgehog genes antagonists such as N-[5-(1H-benzimidazol-2-yl)-6-chloropyridin-3-yl]-2-methyl-6-(trifluoromethyl)pyridine-3-carboxamide, used as anticarcinogenic or antitumor agents | GLI1, SHH, SMO | CRHBP 2240/4885CRHR2 4058/4885ALDH1A1 2356/4885 |
| US-11802122-B2 | 2-oxoimidazolidine-4-carboxamides as NAv1.8 inhibitors | SCN8A, TRPV1, SCN2A | CRHBP 1856/4885CRHR2 1033/4885ALDH1A1 1922/4885 |
| US-20230312528-A1 | 2-OXO-IMIDAZOLIDINE-4-CARBOXAMIDES AS NAV1.8 INHIBITORS | SCN8A, TRPV1, SCN2A | CRHBP 2090/4885CRHR2 1076/4885ALDH1A1 2181/4885 |
| US-20080161347-A1 | Substituted Aryl and Heteroaryl Derivatives, Compositions Containing Such Compounds and Methods of Use | GPR119, PNLIP, SLC5A2 | CRHBP 4378/4885CRHR2 1693/4885ALDH1A1 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.