SCHEMBL2995109

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2995106	1.00	MKNK1 (0.38)	MKNK1MKNK2ROCK2HSD11B1CYP11B2
	SCHEMBL2996682	0.91	MKNK1 (0.39)	MKNK1MKNK2ROCK2HSD11B1CYP11B2
	SCHEMBL2996439	0.91	MKNK1 (0.39)	MKNK1MKNK2ROCK2HSD11B1CYP11B2
	Hydrochloric Acid SCHEMBL3882198	0.90	MKNK1 (0.39)	MKNK1MKNK2ROCK2HSD11B1CYP11B2
	Hydrochloric Acid SCHEMBL3882202	0.90	MKNK1 (0.39)	MKNK1MKNK2ROCK2HSD11B1CYP11B2
	SCHEMBL3001080	0.89	HSD11B1 (0.48)	MKNK1MKNK2ROCK2HSD11B1CYP11B2
	Hydrochloric Acid SCHEMBL3997563	0.88	HSD11B1 (0.47)	MKNK1MKNK2ROCK2HSD11B1CYP11B2
	SCHEMBL2985055	0.85	MKNK1 (0.38)	MKNK1MKNK2ROCK2HSD11B1CYP11B2
	SCHEMBL2985050	0.85	MKNK1 (0.38)	MKNK1MKNK2ROCK2HSD11B1CYP11B2
	SCHEMBL2992049	0.85	MKNK1 (0.38)	MKNK1MKNK2ROCK2HSD11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.