Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15013254 | 0.80 | RAB9A (0.43) | ALDH1A1 | |
| SCHEMBL2253505 | 0.76 | LMNA (0.33) | ALDH1A1 | |
| SCHEMBL15349467 | 0.73 | RAB9A (0.30) | — | |
| SCHEMBL23292148 | 0.71 | RAB9A (0.30) | — | |
| SCHEMBL452296 | 0.71 | CHEK1 (0.32) | — | |
| SCHEMBL2253715 | 0.68 | TNF (0.31) | — | |
| SCHEMBL7329300 | 0.62 | DCTPP1 (0.39) | — | |
| SCHEMBL2257307 | 0.62 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL7331691 | 0.60 | CHEK1 (0.49) | ALDH1A1 | |
| SCHEMBL452454 | 0.60 | F2RL3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121317-A9 | IMIDAZOTHIADIAZOLES FOR USE AS KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO) (ES) | 2012-03-15 | — | — | WO | disclosed |
| WO-2011121317-A1 | IMIDAZO [2,1-B] [1,3,4] THIADIAZOLES AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO) (ES) | 2011-10-06 | — | — | WO | disclosed |