Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955234 | 0.79 | KDM4E (0.44) | KDM4EGPR3ERN1MAPTPDPK1 | |
| SCHEMBL29954370 | 0.79 | MAOA (0.47) | KDM4EGPR3ERN1MAPTPDPK1 | |
| SCHEMBL20600552 | 0.76 | KDM4E (0.52) | KDM4EERN1MAPT | |
| SCHEMBL25203412 | 0.75 | KDM4E (0.40) | KDM4EGPR3ERN1MAPTPDPK1 | |
| SCHEMBL17685059 | 0.75 | POLB (0.52) | KDM4EGPR3ERN1PDPK1ALDH1A1 | |
| SCHEMBL23474020 | 0.75 | GPR3 (0.52) | KDM4EGPR3ERN1TLR7 | |
| SCHEMBL22758237 | 0.72 | KDM4E (0.48) | KDM4EGPR3ERN1PDPK1NCF1 | |
| SCHEMBL31716565 | 0.71 | GPR3 (0.52) | KDM4EGPR3ERN1PDPK1NCF1 | |
| SCHEMBL482068 | 0.71 | NCF1 (0.50) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL11734493 | 0.71 | KDM4E (0.52) | KDM4EGPR3ERN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |