Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 6/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953969 | 0.88 | ALDH1A3 (0.43) | ALDH1A1ALDH1A3ALDH3A1KDM4E | |
| SCHEMBL29955126 | 0.86 | ALDH1A1 (0.43) | ALDH1A1ALDH1A3ALDH3A1KDM4EPOLB | |
| SCHEMBL2555361 | 0.82 | ALDH1A3 (0.38) | ALDH1A1ALDH1A3ALDH3A1KDM4EPOLB | |
| SCHEMBL29951287 | 0.80 | ALDH1A1 (0.53) | ALDH1A1ALDH1A3ALDH3A1KDM4EPOLB | |
| SCHEMBL2562764 | 0.79 | ALDH1A1 (0.40) | ALDH1A1ALDH1A3ALDH3A1KDM4E | |
| SCHEMBL2560265 | 0.78 | ALDH1A1 (0.51) | ALDH1A1ALDH1A3ALDH3A1KDM4EPOLB | |
| SCHEMBL29954725 | 0.77 | ICMT (0.35) | ALDH1A1ALDH1A3ALDH3A1 | |
| SCHEMBL2560571 | 0.75 | ALDH1A1 (0.37) | ALDH1A1ALDH1A3ALDH3A1KDM4E | |
| SCHEMBL29954875 | 0.75 | ALDH1A1 (0.34) | ALDH1A1KDM4EPOLBGAAMEN1 | |
| SCHEMBL29956977 | 0.74 | SLC16A3 (0.40) | ALDH1A1KDM4EPOLBGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |