Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.33 |
| ▸ | SCD | O00767 | 4/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954852 | 0.78 | SCD (0.43) | POLBLRRK2SCDTYK2 | |
| SCHEMBL29955612 | 0.77 | CCR1 (0.37) | CCR1CCR5CCR8POLB | |
| SCHEMBL29952864 | 0.77 | POLB (0.36) | POLBLRRK2SCD | |
| SCHEMBL29951693 | 0.73 | KMO (0.36) | CCR1CCR5CCR8POLBSCD | |
| SCHEMBL29951320 | 0.73 | SCD (0.32) | POLBLRRK2SCDPDE4BCSF1R | |
| SCHEMBL29957690 | 0.73 | LOX (0.38) | CCR1CCR5CCR8POLB | |
| SCHEMBL29954655 | 0.73 | CA1 (0.39) | POLB | |
| SCHEMBL29953450 | 0.72 | PARP10 (0.38) | CCR1CCR5CCR8POLBSCD | |
| SCHEMBL29955258 | 0.71 | POLB (0.36) | POLBCSF1R | |
| SCHEMBL19641310 | 0.69 | CCR1 (0.41) | CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |