Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ASPH | Q12797 | 2/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953450 | 0.87 | PARP10 (0.38) | KMOCCR1CCR5CCR8POLB | |
| SCHEMBL29954852 | 0.83 | SCD (0.43) | POLBSCD | |
| SCHEMBL29955612 | 0.77 | CCR1 (0.37) | CCR1CCR5CCR8POLB | |
| SCHEMBL29958426 | 0.77 | KMO (0.41) | KMOKDM4EASPHKDM8ALDH1A1 | |
| SCHEMBL29957690 | 0.73 | LOX (0.38) | CCR1CCR5CCR8POLB | |
| SCHEMBL29951753 | 0.73 | KMO (0.37) | KMOKDM4EASPHKDM8POLB | |
| SCHEMBL29951305 | 0.73 | CCR1 (0.34) | CCR1CCR5CCR8POLBSCD | |
| SCHEMBL29956893 | 0.73 | CA1 (0.39) | KDM4EALDH1A1ALOX15L3MBTL1POLB | |
| SCHEMBL9459401 | 0.71 | KDM4E (0.47) | KDM4EASPHKDM8CCR1CCR5 | |
| SCHEMBL548552 | 0.71 | KDM4E (0.43) | KDM4EASPHKDM8CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |