Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 4/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 4/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955013 | 0.78 | SCD (0.41) | SCDIDO1HCRTR1HCRTR2AR | |
| SCHEMBL29953312 | 0.77 | ROCK1 (0.36) | POLBIDO1KMOHCRTR1HCRTR2 | |
| SCHEMBL29951407 | 0.77 | POLB (0.36) | POLBSCDIDO1KMOAR | |
| SCHEMBL29951305 | 0.77 | CCR1 (0.34) | POLBSCDLRRK2 | |
| SCHEMBL29958426 | 0.73 | KMO (0.41) | POLBIDO1KMOHCRTR1HCRTR2 | |
| SCHEMBL29951188 | 0.73 | LOX (0.38) | POLBSCDIDO1HCRTR1HCRTR2 | |
| SCHEMBL28852814 | 0.73 | GRM5 (0.40) | SCDKAT2BBAZ2B | |
| SCHEMBL29956373 | 0.73 | KAT2B (0.38) | POLBKAT2BBAZ2BRORC | |
| SCHEMBL29955574 | 0.72 | MKNK1 (0.38) | SCDIDO1KMOHCRTR1HCRTR2 | |
| SCHEMBL16101275 | 0.71 | ALDH1A1 (0.43) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |