Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951693 | 0.87 | KMO (0.36) | SCDCCR1CCR5CCR8POLB | |
| SCHEMBL29954852 | 0.82 | SCD (0.43) | SCDBRAFPOLB | |
| SCHEMBL29955612 | 0.79 | CCR1 (0.37) | CCR1CCR5CCR8POLBKCNH2 | |
| SCHEMBL29955574 | 0.77 | MKNK1 (0.38) | PARP10OPRM1MAP4K4SCDMKNK1 | |
| SCHEMBL29957690 | 0.75 | LOX (0.38) | CCR1CCR5CCR8POLB | |
| SCHEMBL29955125 | 0.74 | PARP10 (0.41) | PARP10MAP4K4SCDMKNK1MKNK2 | |
| SCHEMBL29952660 | 0.74 | PARP10 (0.40) | PARP10MKNK1MKNK2OPRK1KCNH2 | |
| SCHEMBL29951305 | 0.72 | CCR1 (0.34) | SCDCCR1CCR5CCR8GSK3B | |
| SCHEMBL29953303 | 0.71 | MAP4K4 (0.42) | PARP10MAP4K4MKNK1MKNK2SENP8 | |
| SCHEMBL29956486 | 0.70 | MAP4K4 (0.40) | PARP10MAP4K4MKNK1MKNK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |