Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953704 | 0.86 | MAPT (0.53) | MAPTRAB9ANPC1SMN1; SMN2TAAR1 | |
| SCHEMBL29955344 | 0.83 | KMT2A (0.56) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11270620 | 0.83 | MTOR (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11279243 | 0.82 | MEN1 (0.47) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL29950920 | 0.81 | RAB9A (0.55) | MAPTRAB9ANPC1SMN1; SMN2TAAR1 | |
| SCHEMBL2562508 | 0.79 | LMNA (0.65) | MAPTRAB9ANPC1SMN1; SMN2TAAR1 | |
| SCHEMBL11284371 | 0.75 | APEX1 (0.67) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL2556599 | 0.74 | MAPT (0.62) | MAPTRAB9ANPC1SMN1; SMN2TAAR1 | |
| SCHEMBL11171828 | 0.73 | MAPT (0.50) | MAPTRAB9ANPC1SMN1; SMN2TAAR1 | |
| SCHEMBL3825140 | 0.73 | MAPT (0.68) | MAPTRAB9ANPC1SMN1; SMN2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |