Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951487 | 0.86 | MAPT (0.51) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29950970 | 0.84 | KMT2A (0.55) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2561693 | 0.77 | MAPT (0.68) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21820774 | 0.76 | ALDH1A1 (0.59) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7566026 | 0.74 | ALDH1A1 (0.66) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27892102 | 0.74 | MAPT (0.64) | MAPTALDH1A1SMN1; SMN2NPC1MEN1 | |
| SCHEMBL29950920 | 0.74 | RAB9A (0.55) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21820792 | 0.74 | ALDH1A1 (0.56) | ALDH1A1RAB9ANPY5RPOLBGAA | |
| SCHEMBL29952991 | 0.73 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2556599 | 0.73 | MAPT (0.62) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |