SCHEMBL11279243

SCHEMBL11279243

CN(CC(=O)O)C(=O)Nc1ccc(F)cc1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
POLB P06746 1/20 0.47
MTOR P42345 2/20 0.47
ALDH1A1 P00352 4/20 0.46
LMNA P02545 2/20 0.46
GAA P10253 3/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
THRB P10828 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
MITF O75030 1/20 0.44
NPY5R Q15761 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11270620 0.84 MTOR (0.59) MEN1KMT2AMTORALDH1A1GAA
SCHEMBL29951487 0.82 MAPT (0.51) MEN1KMT2APOLBALDH1A1LMNA
SCHEMBL10470766 0.80 PKM (0.49) MEN1KMT2APOLBMTORALDH1A1
SCHEMBL12292880 0.78 TSHR (0.66) MEN1KMT2APOLBALDH1A1LMNA
SCHEMBL10670279 0.78 ALDH1A1 (0.51) MEN1KMT2AALDH1A1LMNAGAA
SCHEMBL7616725 0.77 GAA (0.59) MEN1KMT2APOLBALDH1A1LMNA
SCHEMBL11284371 0.76 APEX1 (0.67) MEN1KMT2APOLBALDH1A1LMNA
SCHEMBL13811051 0.75 ICMT (0.57) KMT2AALDH1A1LMNAGAANPC1
SCHEMBL10573342 0.74 ALDH1A1 (0.52) ALDH1A1LMNAGAANPC1RAB9A
SCHEMBL13060491 0.74 RAB9A (0.62) MEN1KMT2APOLBALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4360672-A Substituted phenoxyphenyl pyridazones, their preparation, and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1982-11-23 US disclosed