SCHEMBL29951580

SCHEMBL29951580

COc1cc(B(O)O)ccc1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.44
ENPP2 Q13822 5/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
KDR P35968 3/20 0.36
TUBB4A P04350 4/20 0.33
TUBB P07437 4/20 0.33
TUBA3C P0DPH7 4/20 0.33
TUBA1B P68363 4/20 0.33
TUBA4A P68366 4/20 0.33
TUBB4B P68371 4/20 0.33
TUBB3 Q13509 4/20 0.33
TUBB2A Q13885 4/20 0.33
TUBB8 Q3ZCM7 4/20 0.33
TUBA3E Q6PEY2 4/20 0.33
TUBA1A Q71U36 4/20 0.33
TUBA1C Q9BQE3 4/20 0.33
TUBB6 Q9BUF5 4/20 0.33
TUBB2B Q9BVA1 4/20 0.33
TUBB1 Q9H4B7 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16564308 1.00 DRD2 (0.44) DRD2ENPP2CA1CA2KDR
SCHEMBL14721223 0.94 DRD2 (0.39) DRD2ENPP2CA1CA2KDR
SCHEMBL4621217 0.84 DRD2 (0.33) DRD2ENPP2
SCHEMBL21751397 0.81 TTR (0.38) DRD2ENPP2CA1CA2CA12
SCHEMBL12639825 0.81 DRD2 (0.37) DRD2ENPP2TSHRALDH1A1HPGD
SCHEMBL23114 0.79 ENPP2 (0.52) ENPP2CA1CA2KDRTUBB4A
SCHEMBL6049222 0.79 MAOB (0.48) DRD2CYP3A4ALDH1A1KMT2A
SCHEMBL5331625 0.79 ENPP2 (0.36) ENPP2CA1CA2KDRCYP1A2
SCHEMBL31737879 0.79 ENPP2 (0.36) ENPP2CA1CA2KDRCYP1A2
SCHEMBL6451525 0.78 LIPE (0.47) ENPP2CYP1A2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed