Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564308 | 0.84 | DRD2 (0.44) | DRD2ENPP2 | |
| SCHEMBL29951580 | 0.84 | DRD2 (0.44) | DRD2ENPP2 | |
| SCHEMBL14721223 | 0.81 | DRD2 (0.39) | DRD2ENPP2 | |
| SCHEMBL4621189 | 0.79 | APLNR (0.39) | DRD2 | |
| SCHEMBL21751397 | 0.78 | TTR (0.38) | DRD2ENPP2 | |
| SCHEMBL12639825 | 0.77 | DRD2 (0.37) | DRD2ENPP2 | |
| SCHEMBL5636990 | 0.77 | ENPP2 (0.42) | ENPP2 | |
| SCHEMBL6451525 | 0.75 | LIPE (0.47) | ENPP2 | |
| SCHEMBL15770495 | 0.74 | ENPP2 (0.35) | DRD2ENPP2 | |
| SCHEMBL6450570 | 0.73 | MAPK1 (0.35) | DRD2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896462-A2 | SUBSTITUTED BIARYLHETEROCYCLE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | The Pfahl Family Trust (Dated 9 July 1996) (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006130613-A2 | SUBSTITUTED BIARYLHETEROCYCLE DERIVATIVES AS PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF CANCER AND OTHER DISEASES | THE PFAHL FAMILY TRUST (DATED 9 JULY 1996) (US) | 2006-12-07 | — | — | WO | disclosed |