Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22672276 | 0.83 | HPGD (0.40) | MEN1KMT2A | |
| SCHEMBL607884 | 0.74 | APLNR (0.40) | APLNRAURKATTKAURKBINCENP | |
| SCHEMBL29951535 | 0.72 | TRPV4 (0.38) | — | |
| SCHEMBL29954143 | 0.72 | NPC1 (0.31) | — | |
| SCHEMBL21549572 | 0.71 | POLB (0.37) | — | |
| SCHEMBL4794 | 0.70 | ENPP2 (0.47) | ENPP2APLNR | |
| SCHEMBL29489857 | 0.70 | ENPP2 (0.47) | ENPP2APLNR | |
| SCHEMBL26227332 | 0.69 | — | — | |
| SCHEMBL29951673 | 0.69 | — | — | |
| Water SCHEMBL1543573 | 0.68 | ENPP2 (0.45) | ENPP2APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |