Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 8/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957063 | 0.81 | RORC (0.36) | CRHR1KDM4EHSD17B10RORCMLYCD | |
| SCHEMBL29952351 | 0.80 | CYP1A2 (0.46) | CRHR1RORCCRHR2 | |
| SCHEMBL29955127 | 0.76 | HDAC3 (0.44) | SLC6A2SLC6A4RORC | |
| SCHEMBL29951189 | 0.74 | SLC6A4 (0.58) | SLC6A2SLC6A4 | |
| SCHEMBL29956670 | 0.71 | DPP4 (0.42) | SLC6A2SLC6A4 | |
| SCHEMBL29952171 | 0.69 | ALDH1A1 (0.46) | SLC6A2SLC6A4KDM4E | |
| SCHEMBL29957787 | 0.68 | SLC6A4 (0.51) | SLC6A2SLC6A4 | |
| SCHEMBL2560574 | 0.67 | ALDH1A1 (0.48) | KDM4E | |
| SCHEMBL13649148 | 0.66 | OPRM1 (0.55) | RORC | |
| SCHEMBL8252184 | 0.65 | HRH3 (0.52) | CRHR1KDM4EHSD17B10RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |