Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 8/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951606 | 0.81 | CRHR1 (0.42) | RORCCRHR1MLYCDKDM4EHSD17B10 | |
| SCHEMBL29952351 | 0.79 | CYP1A2 (0.46) | RORCCRHR1DRD2DRD3CYP1A2 | |
| SCHEMBL29958472 | 0.75 | SLC6A2 (0.48) | DRD2DRD3 | |
| SCHEMBL29956262 | 0.72 | SLC6A2 (0.40) | RORCCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30643134 | 0.72 | KDM4E (0.44) | CYP1A2CYP2C9CYP2C19KDM4EHSD17B10 | |
| SCHEMBL29957424 | 0.70 | ALDH1A1 (0.45) | RORCHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL18393729 | 0.70 | LIPG (0.50) | — | |
| SCHEMBL17485375 | 0.70 | LPL (0.47) | — | |
| SCHEMBL29954644 | 0.69 | SLC6A2 (0.44) | — | |
| SCHEMBL29954950 | 0.69 | HTR1A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |