SCHEMBL29951676

SCHEMBL29951676

CCCc1ccncc1C=O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2E1 P05181 6/20 0.44
CYP2C8 P10632 6/20 0.44
CYP2D6 P10635 6/20 0.44
CYP2A6 P11509 6/20 0.44
CYP2B6 P20813 6/20 0.44
CYP2C19 P33261 6/20 0.44
CYP2C9 P11712 5/20 0.44
CYP1A2 P05177 4/20 0.40
CYP3A4 P08684 3/20 0.40
AOC1 P19801 5/20 0.38
AOC3 Q16853 5/20 0.38
KDM4C Q9H3R0 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SLC6A2 P23975 1/20 0.33
CCNT1 O60563 1/20 0.33
CDK9 P50750 1/20 0.33
HASPIN Q8TF76 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250163 0.89 TDP1 (0.39) CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6
SCHEMBL4564968 0.88 TDP1 (0.45) CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6
SCHEMBL31068616 0.86 CYP2A6 (0.42) CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6
SCHEMBL14872350 0.86 CYP2A6 (0.42) CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6
SCHEMBL19316061 0.79 CYP2E1 (0.42) CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6
SCHEMBL29958096 0.77 AOC1 (0.35) CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6
SCHEMBL8271491 0.76 CYP2E1 (0.49) CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6
SCHEMBL7468680 0.76 CYP2E1 (0.49) CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6
SCHEMBL10954433 0.76 CYP2E1 (0.51) CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6
SCHEMBL29952188 0.75 CCNC (0.40) CYP2E1CYP2C8CYP2D6CYP2A6CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed