Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558403 | 0.82 | AKR1C3 (0.37) | KDM4ETSHRGAAMEN1KMT2A | |
| SCHEMBL2558400 | 0.82 | AKR1C3 (0.37) | KDM4ETSHRGAAMEN1KMT2A | |
| SCHEMBL29954348 | 0.82 | MTNR1A (0.45) | KDM4EALDH1A1HPGDPDE4BADRA2A | |
| SCHEMBL29957552 | 0.82 | MAPT (0.47) | KDM4ETSHRGAAMEN1KMT2A | |
| SCHEMBL22215851 | 0.80 | KDM4E (0.46) | KDM4ETSHRGAAMEN1KMT2A | |
| SCHEMBL1490739 | 0.79 | MAPT (0.45) | KDM4ETSHRGAAMEN1KMT2A | |
| SCHEMBL29956763 | 0.79 | MAPT (0.45) | KDM4ETSHRGAAMEN1KMT2A | |
| SCHEMBL8161827 | 0.79 | SMN1; SMN2 (0.45) | KDM4ETSHRGAAMEN1KMT2A | |
| SCHEMBL15329658 | 0.78 | KMT2A (0.40) | KDM4ETSHRGAAMEN1KMT2A | |
| SCHEMBL28821754 | 0.77 | LIPE (0.56) | KDM4ETSHRALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |