Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 8/20 | 0.46 |
| ▸ | HTR2A | P28223 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558775 | 0.83 | AKR1C3 (0.36) | MAPTL3MBTL1HTR2CHTR2AMAPK1 | |
| SCHEMBL29955810 | 0.83 | MTNR1A (0.44) | MAPTKDM4EHPGDMAPK1ALDH1A1 | |
| SCHEMBL2558777 | 0.83 | AKR1C3 (0.36) | MAPTL3MBTL1HTR2CHTR2AMAPK1 | |
| SCHEMBL29951691 | 0.82 | KDM4E (0.41) | MAPTKDM4ETSHRGAAMEN1 | |
| SCHEMBL15329658 | 0.80 | KMT2A (0.40) | MAPTL3MBTL1KDM4ETSHRGAA | |
| SCHEMBL29952296 | 0.80 | L3MBTL1 (0.42) | L3MBTL1TSHRMEN1KMT2AHSD17B10 | |
| SCHEMBL1440694 | 0.80 | L3MBTL1 (0.42) | L3MBTL1TSHRMEN1KMT2AHSD17B10 | |
| SCHEMBL28821754 | 0.80 | LIPE (0.56) | MAPTL3MBTL1HTR2AKDM4ETSHR | |
| SCHEMBL15331160 | 0.77 | PKM (0.40) | MAPTL3MBTL1HTR2CHTR2AKDM4E | |
| SCHEMBL263259 | 0.77 | HTR2C (0.46) | MAPTL3MBTL1HTR2CHTR2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |