Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953581 | 0.94 | GPR17 (0.36) | GPR17 | |
| SCHEMBL29957613 | 0.86 | NOS2 (0.40) | NOS1NOS2HTR2AHTR2CKCNH2 | |
| SCHEMBL29955937 | 0.86 | AR (0.32) | KCNH2DYRK1A | |
| SCHEMBL29954981 | 0.81 | AR (0.35) | HTR2AHTR2CKCNH2 | |
| SCHEMBL29956616 | 0.81 | MEN1 (0.41) | DYRK1A | |
| SCHEMBL29955949 | 0.80 | NOS2 (0.36) | NOS1NOS2 | |
| SCHEMBL29956885 | 0.80 | MEN1 (0.32) | — | |
| SCHEMBL29956872 | 0.79 | HTT (0.33) | KCNH2DYRK1A | |
| SCHEMBL29954328 | 0.78 | AR (0.35) | NOS1NOS2 | |
| SCHEMBL29951772 | 0.78 | DYRK1A (0.40) | NOS1NOS2HTR2AHTR2CKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |