Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956527 | 0.92 | HTT (0.35) | HTTPTK2BMEN1ALDH1A1KMT2A | |
| SCHEMBL29955937 | 0.81 | AR (0.32) | CYP2D6SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL29956616 | 0.81 | MEN1 (0.41) | SLC6A4MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL29951787 | 0.79 | GPR17 (0.34) | KCNH2DYRK1A | |
| SCHEMBL29954538 | 0.77 | FFAR2 (0.34) | DYRK1AJAK2JAK1TYK2JAK3 | |
| SCHEMBL29957069 | 0.77 | KDM4E (0.38) | MEN1ALDH1A1KMT2ADYRK1AJAK2 | |
| SCHEMBL29950851 | 0.75 | MEN1 (0.34) | MEN1ALDH1A1KMT2A | |
| SCHEMBL29955079 | 0.75 | MEN1 (0.43) | SLC6A4KCNH2MEN1ALDH1A1KMT2A | |
| SCHEMBL29956885 | 0.75 | MEN1 (0.32) | MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL29957291 | 0.74 | MEN1 (0.38) | CYP2D6MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |