Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.50 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.50 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.50 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2645341 | 1.00 | MGLL (0.61) | MGLLCA1CA2TRPV6ORAI1 | |
| SCHEMBL29957058 | 0.94 | MGLL (0.63) | MGLLCA1CA2TRPV6ORAI1 | |
| SCHEMBL2644437 | 0.94 | MGLL (0.63) | MGLLCA1CA2TRPV6ORAI1 | |
| SCHEMBL28784898 | 0.81 | CA2 (0.76) | MGLLCA1CA2ENPP2KDM4E | |
| SCHEMBL4179 | 0.77 | MGLL (1.00) | MGLLCA1CA2TRPV6ORAI1 | |
| SCHEMBL15947198 | 0.74 | CA2 (0.55) | MGLLCA1CA2ENPP2MEN1 | |
| SCHEMBL29951609 | 0.74 | CA2 (0.55) | MGLLCA1CA2ENPP2MEN1 | |
| SCHEMBL31651429 | 0.74 | MGLL (0.43) | MGLLCA1CA2TRPV6ORAI1 | |
| SCHEMBL29382879 | 0.74 | MGLL (0.47) | MGLLTRPV6ORAI1ORAI2ORAI3 | |
| SCHEMBL12895889 | 0.74 | BACE1 (0.52) | PTPN1BACE1KDM4EMETAP2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |