Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951975 | 0.78 | POLB (0.38) | UGCGSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL29956327 | 0.76 | NPC1 (0.53) | NPC1RAB9APKMTP53SMN1; SMN2 | |
| SCHEMBL29951234 | 0.74 | NOTUM (0.45) | SMN1; SMN2MEN1KMT2ACYP2D6HTT | |
| SCHEMBL29957027 | 0.74 | HTT (0.44) | MEN1KMT2AHTT | |
| SCHEMBL29951946 | 0.74 | IDH1 (0.44) | NPC1MEN1KMT2AHTT | |
| SCHEMBL21212756 | 0.73 | UGCG (0.55) | UGCGNPC1RAB9A | |
| SCHEMBL28360719 | 0.72 | UGCG (0.53) | UGCGNPC1RAB9APKMMEN1 | |
| SCHEMBL29954152 | 0.72 | HTT (0.43) | RAB9AMEN1KMT2ALMNAGAA | |
| SCHEMBL2558098 | 0.72 | PARP1 (0.41) | NPC1RAB9AMEN1KMT2ALMNA | |
| SCHEMBL30083042 | 0.71 | HTR7 (0.50) | UGCGNPC1RAB9ALMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |