Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.42 |
| ▸ | ADH1A | P07327 | 1/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
| ▸ | ADH7 | P40394 | 1/20 | 0.42 |
| ▸ | DNM2 | P50570 | 6/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953824 | 0.93 | HCAR3 (0.41) | HDAC1HDAC8HDAC3HDAC2ADH1B | |
| SCHEMBL29958427 | 0.85 | ACACB (0.38) | HDAC1HDAC8HDAC3HDAC2ADH1B | |
| SCHEMBL18611842 | 0.80 | DNM2 (0.47) | HDAC1HDAC8HDAC3HDAC2DNM2 | |
| SCHEMBL20341674 | 0.79 | KMT2A (0.45) | HDAC1HDAC8HDAC3HDAC2DNM2 | |
| SCHEMBL29958007 | 0.77 | ALDH1A1 (0.41) | HCAR3KMT2ALMNA | |
| SCHEMBL8143978 | 0.76 | DNM2 (0.39) | DNM2HCAR3KCNH3KMT2AFLT3 | |
| SCHEMBL28413722 | 0.76 | KMT2A (0.42) | DNM2HCAR3KCNH3KMT2ANPSR1 | |
| SCHEMBL25097601 | 0.76 | DNM2 (0.41) | HDAC1HDAC8HDAC3HDAC2DNM2 | |
| SCHEMBL23610609 | 0.76 | ALDH1A1 (0.60) | DNM2KCNH3KMT2AS1PR2LMNA | |
| SCHEMBL10532570 | 0.76 | ALDH1A1 (0.60) | DNM2KCNH3KMT2AS1PR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |