Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 7/20 | 0.39 |
| ▸ | MERTK | Q12866 | 7/20 | 0.39 |
| ▸ | FLT3 | P36888 | 6/20 | 0.39 |
| ▸ | GAS6 | Q14393 | 6/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951944 | 0.93 | HDAC1 (0.43) | HCAR3HDAC3TYRO3MERTKFLT3 | |
| SCHEMBL29958427 | 0.89 | ACACB (0.38) | HCAR3HDAC3CA1CA2CA9 | |
| SCHEMBL29958007 | 0.80 | ALDH1A1 (0.41) | HCAR3L3MBTL1 | |
| SCHEMBL29951767 | 0.77 | HCAR3 (0.59) | HCAR3L3MBTL1HRH4TLR8HDAC1 | |
| SCHEMBL27081560 | 0.77 | GAA (0.40) | HDAC3TYRO3MERTKFLT3GAS6 | |
| SCHEMBL27083128 | 0.76 | HCAR3 (0.42) | HCAR3 | |
| SCHEMBL26559480 | 0.75 | — | — | |
| SCHEMBL22242622 | 0.74 | PCSK9 (0.47) | HCAR3HDAC3TYRO3MERTKFLT3 | |
| SCHEMBL6490227 | 0.74 | ALDH1A1 (0.65) | TYRO3MERTKFLT3GAS6AXL | |
| SCHEMBL2556214 | 0.74 | ALDH1A1 (0.44) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |