Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955556 | 0.87 | MAOB (0.39) | HPGDTSHRKMT2ASRCPDE4B | |
| SCHEMBL28342817 | 0.84 | ALDH1A1 (0.44) | HPGDTSHRKMT2ASRCALDH1A1 | |
| SCHEMBL29470912 | 0.81 | TSHR (0.42) | HPGDTSHRKMT2APDE4BALDH1A1 | |
| SCHEMBL4936956 | 0.81 | HPGD (0.67) | HPGDTSHRKMT2AALDH1A1LMNA | |
| SCHEMBL28420547 | 0.81 | ALDH1A1 (0.47) | HPGDTSHRALDH1A1PTGDR2HTT | |
| SCHEMBL29953871 | 0.80 | LMNA (0.51) | HPGDTSHRKMT2ASRCALDH1A1 | |
| SCHEMBL15630177 | 0.80 | LMNA (0.51) | HPGDTSHRKMT2ASRCALDH1A1 | |
| SCHEMBL25528508 | 0.78 | SMN1; SMN2 (0.45) | HPGDTSHRKMT2AALDH1A1LMNA | |
| SCHEMBL30852959 | 0.77 | CA12 (0.41) | HPGDKMT2ASRCALDH1A1MEN1 | |
| SCHEMBL14607940 | 0.77 | KDM4E (0.48) | HPGDTSHRKMT2ASRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |