Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 4/20 | 0.36 |
| ▸ | TLR4 | O00206 | 3/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958065 | 0.90 | MAPT (0.43) | MAPTRAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL4348230 | 0.81 | ESR2 (0.47) | MAPTRAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL18114435 | 0.81 | RAB9A (0.63) | MAPTRAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL212819 | 0.75 | RAB9A (0.60) | MAPTRAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL29957899 | 0.74 | PIK3CA (0.48) | MAPTRAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7898012 | 0.74 | PIK3CA (0.48) | MAPTRAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7898364 | 0.74 | LCK (0.59) | RAB9ASMN1; SMN2NPC1TP53ABL1 | |
| SCHEMBL15738098 | 0.73 | ALDH1A1 (0.48) | MAPTRAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL18114422 | 0.72 | AGPAT2 (0.50) | MAPTRAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL21612949 | 0.71 | XDH (0.47) | MAPTRAB9AKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |