Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952347 | 0.90 | MAPT (0.43) | MAPTRAB9ASMN1; SMN2TP53ENPP2 | |
| SCHEMBL18114422 | 0.82 | AGPAT2 (0.50) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL29974587 | 0.81 | RAB9A (0.64) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL21612949 | 0.81 | XDH (0.47) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL210184 | 0.81 | RAB9A (0.64) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL10829024 | 0.81 | MAPT (0.56) | MAPTRAB9ASMN1; SMN2TP53NPSR1 | |
| SCHEMBL26654543 | 0.81 | RAB9A (0.50) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL17161464 | 0.77 | AGPAT2 (0.52) | MAPTRAB9ASMN1; SMN2TP53HDAC6 | |
| SCHEMBL212819 | 0.76 | RAB9A (0.60) | MAPTRAB9ASMN1; SMN2TP53NPC1 | |
| SCHEMBL21360027 | 0.74 | MAPT (0.39) | MAPTRAB9ASMN1; SMN2TP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |