Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25786898 | 0.75 | MME (0.41) | NPSR1KMT2ALMNAHTTL3MBTL1 | |
| SCHEMBL18091512 | 0.72 | BRD4 (0.35) | NPSR1ADRA2AADRA2BADRA2CADRA1B | |
| SCHEMBL20975606 | 0.71 | NOTUM (0.34) | LMNAHTTL3MBTL1NOTUM | |
| SCHEMBL29448021 | 0.70 | KMT2A (0.44) | NPSR1ADRA2AADRA2BADRA2CADRA1B | |
| SCHEMBL11529778 | 0.70 | KMT2A (0.44) | NPSR1ADRA2AADRA2BADRA2CADRA1B | |
| SCHEMBL23874419 | 0.70 | GHSR (0.35) | KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL11537869 | 0.69 | KDM4E (0.44) | NPSR1ADRA2AADRA2BADRA2CADRA1B | |
| SCHEMBL2090676 | 0.68 | MEN1 (0.34) | NPSR1ADRA2AADRA2BADRA2CKMT2A | |
| SCHEMBL3659892 | 0.67 | HDAC9 (0.37) | NPSR1LMNAHTTL3MBTL1ALDH1A1 | |
| SCHEMBL865212 | 0.67 | ADRA2A (0.41) | NPSR1ADRA2AADRA2BADRA2CADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658639-A1 | N,N-DIALKYL-4-(2-ETHYLINDAN-2-YL)-1H-IMIDAZOLE-1-CARBOXAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | Univerza V Ljubljani (SI) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024160908-A1 | N,N-DIALKYL-4-(2-ETHYLINDAN-2-YL)-1H-IMIDAZOLE-1-CARBOXAMIDES AND RELATED COMPOUNDS FOR TREATMENT OF NEURODEGENERATIVE DISEASES | UNIVERZA V LJUBLJANI (SI) | 2024-08-08 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |