Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718368 | 0.77 | TSHR (0.39) | HDAC9NOTUMTSHR | |
| SCHEMBL32683479 | 0.76 | ADRA1D (0.35) | HDAC9CA1CA2TSHR | |
| SCHEMBL6023073 | 0.76 | ADRA1D (0.35) | HDAC9CA1CA2TSHR | |
| SCHEMBL11844628 | 0.71 | ALDH1A1 (0.35) | HDAC9CYP1A2L3MBTL1LMNAHTT | |
| SCHEMBL20975606 | 0.71 | NOTUM (0.34) | HDAC9CYP1A2L3MBTL1LMNAHTT | |
| SCHEMBL8162156 | 0.71 | HDAC9 (0.39) | HDAC9CYP1A2MMECA1CA2 | |
| SCHEMBL2090676 | 0.68 | MEN1 (0.34) | HDAC9CYP1A2L3MBTL1LMNAHTT | |
| SCHEMBL12083387 | 0.67 | L3MBTL1 (0.49) | L3MBTL1LMNAHTTNPSR1ALDH1A1 | |
| SCHEMBL25786898 | 0.67 | MME (0.41) | HDAC9MMEL3MBTL1LMNAHTT | |
| SCHEMBL4644536 | 0.67 | HTR2A (0.37) | HDAC9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2209547-B1 | OZONOLYSIS REACTIONS IN LIQUID CO2 AND CO2-EXPANDED SOLVENTS | UNIV KANSAS (US) | 2018-06-20 | — | — | EP | disclosed |
| CN-101909729-B | Ozonolysis reactions in liquid CO2 and CO2-expanded solvents | UNIVERSITY OF KANSAS (US) | 2014-10-22 | — | — | CN | disclosed |
| US-8801939-B2 | Ozonolysis reactions in liquid CO2 and CO2-expanded solvents | UNIVERSITY OF KANSAS (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130240781-A1 | Ozonolysis Reactions in Liquid CO2 and CO2-Expanded Solvents | ARCHER DANIELS MIDLAND COMPANY (US) | 2013-09-19 | — | — | US | disclosed |
| US-8425784-B2 | Ozonolysis reactions in liquid CO2 and CO2-expanded solvents | UNIVERSITY OF KANSAS (US) | 2013-04-23 | — | — | US | disclosed |
| EP-2209547-A2 | OZONOLYSIS REACTIONS IN LIQUID CO2 AND CO2-EXPANDED SOLVENTS | University Of Kansas (US) | 2010-07-28 | — | — | EP | disclosed |
| WO-2009061806-A2 | OZONOLYSIS REACTIONS IN LIQUID CO2 AND CO2-EXPANDED SOLVENTS | UNIVERSITY OF KANSAS (US) | 2009-05-14 | — | — | WO | disclosed |
| US-20090118498-A1 | OZONOLYSIS REACTIONS IN LIQUID CO2 AND CO2-EXPANDED SOLVENTS | ARCHER DANIELS MIDLAND COMPANY | 2009-05-07 | — | — | US | disclosed |
| CN-1867548-A | Preparation of 3-azabicyclo [3.1.0] hexane derivatives | PFIZER (US) | 2006-11-22 | — | — | CN | disclosed |
| US-7129263-B2 | Preparation of 3-azabicyclo [3.1.0] hexane derivatives | PFIZER INC. | 2006-10-31 | — | — | US | disclosed |
| EP-1675829-A1 | PREPARATION OF 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES | Pfizer Products Inc. (US) | 2006-07-05 | — | — | EP | disclosed |
| US-20050113437-A1 | Preparation of 3-azabicyclo [3.1.0] hexane derivatives | PFIZER INC. | 2005-05-26 | — | — | US | disclosed |
| WO-2005037790-A1 | PREPARATION OF 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113437-A1 | Preparation of 3-azabicyclo [3.1.0] hexane derivatives | ADH1C, ADH1A, ADH5 | HDAC9 368/4885CYP1A2 74/4885MME 4422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.