Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 3/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894725 | 1.00 | TDP1 (0.60) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL28231121 | 0.85 | ALDH1A1 (0.60) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL1800032 | 0.78 | ERN1 (0.65) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL16838212 | 0.78 | ALDH5A1 (0.59) | ALDH1A1CYP3A4ALOX15HSD17B10MAPT | |
| SCHEMBL1254184 | 0.77 | TDP1 (0.72) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL371170 | 0.77 | TSHR (0.62) | TSHRALDH1A1CYP3A4ALOX15HSD17B10 | |
| SCHEMBL40312 | 0.77 | MAPK1 (0.60) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL274241 | 0.77 | ERN1 (0.50) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL4941247 | 0.77 | CYP3A4 (0.47) | TDP1TSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL1014901 | 0.77 | BACE1 (0.63) | ALDH1A1CYP3A4ALOX15HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |