Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951533 | 0.88 | NPC1 (0.68) | RAB9ANPC1KMT2AMEN1MAOB | |
| SCHEMBL722066 | 0.85 | MEN1 (0.73) | RAB9ANPC1HTR2BKMT2AMEN1 | |
| SCHEMBL2555750 | 0.85 | NPC1 (0.69) | RAB9ANPC1KMT2AMEN1KCNK3 | |
| SCHEMBL29894244 | 0.85 | MAPT (0.64) | RAB9ANPC1HTR2BKMT2AMEN1 | |
| SCHEMBL28687053 | 0.85 | MAPT (0.64) | RAB9ANPC1HTR2BKMT2AMEN1 | |
| SCHEMBL29954699 | 0.82 | RHOC (0.54) | RAB9ANPC1KMT2AMEN1KCNK3 | |
| SCHEMBL29894462 | 0.81 | HTR2B (0.65) | RAB9ANPC1HTR2BKMT2AMEN1 | |
| SCHEMBL28670681 | 0.81 | HTR2B (0.65) | RAB9ANPC1HTR2BKMT2AMEN1 | |
| SCHEMBL29894358 | 0.81 | PTK2B (0.51) | RAB9ANPC1HTR2BKMT2AMEN1 | |
| SCHEMBL28667305 | 0.81 | PTK2B (0.51) | RAB9ANPC1HTR2BKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |