Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | FADS1 | O60427 | 1/20 | 0.52 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952403 | 0.88 | RAB9A (0.66) | NPC1RAB9ASMN1; SMN2KCNQ3KCNQ2 | |
| SCHEMBL29954699 | 0.85 | RHOC (0.54) | NPC1RAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL2555750 | 0.82 | NPC1 (0.69) | NPC1RAB9AL3MBTL1SMN1; SMN2MAOB | |
| SCHEMBL722066 | 0.82 | MEN1 (0.73) | NPC1RAB9AKCNQ3KCNQ2KCNE1 | |
| SCHEMBL2560439 | 0.81 | FADS1 (0.58) | NPC1RAB9AL3MBTL1SMN1; SMN2FADS1 | |
| SCHEMBL19479147 | 0.81 | NPC1 (0.72) | NPC1RAB9AL3MBTL1SMN1; SMN2FADS1 | |
| SCHEMBL21990931 | 0.81 | NPC1 (0.72) | NPC1RAB9AL3MBTL1SMN1; SMN2FADS1 | |
| SCHEMBL17803524 | 0.81 | NPC1 (0.72) | NPC1RAB9AL3MBTL1SMN1; SMN2FADS1 | |
| SCHEMBL17803482 | 0.81 | NPC1 (0.76) | NPC1RAB9AL3MBTL1SMN1; SMN2FADS1 | |
| SCHEMBL19156827 | 0.81 | NPC1 (0.72) | NPC1RAB9AL3MBTL1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |