Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 1/20 | 0.54 |
| ▸ | RHOA | P61586 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1933481 | 0.86 | HDAC1 (0.63) | KCNK3MEN1KMT2AMAPTTRPV1 | |
| SCHEMBL722066 | 0.85 | MEN1 (0.73) | KCNK3MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL27194943 | 0.85 | SMN1; SMN2 (0.63) | KCNK3MEN1KMT2ATP53KDM4E | |
| SCHEMBL29951533 | 0.85 | NPC1 (0.68) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL29952403 | 0.82 | RAB9A (0.66) | KCNK3MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL3674558 | 0.82 | KCNK3 (0.71) | KCNK3MEN1KMT2ATP53KDM4E | |
| SCHEMBL2556521 | 0.81 | LMNA (0.57) | MEN1KMT2AALDH1A1MAPTNPC1 | |
| SCHEMBL2560174 | 0.81 | TRPV1 (0.67) | MEN1KMT2ATRPV1NPC1RAB9A | |
| SCHEMBL16516375 | 0.80 | CNR1 (0.63) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL2555750 | 0.79 | NPC1 (0.69) | KCNK3MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |