Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.39 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953259 | 0.94 | KDM4E (0.48) | MTNR1AMTNR1BHSD17B10KDM4EKMT2A | |
| SCHEMBL29951013 | 0.86 | MTNR1A (0.55) | MTNR1AMTNR1BHSD17B10KDM4EKMT2A | |
| SCHEMBL1429356 | 0.86 | MTNR1A (0.55) | MTNR1AMTNR1BHSD17B10KDM4EKMT2A | |
| SCHEMBL1428728 | 0.85 | MTNR1A (0.54) | MTNR1AMTNR1BHSD17B10KDM4EKMT2A | |
| SCHEMBL1428978 | 0.84 | MTNR1A (0.52) | MTNR1AMTNR1BHSD17B10KDM4EKMT2A | |
| SCHEMBL29957756 | 0.80 | ALDH1A1 (0.50) | MTNR1AMTNR1BHSD17B10KDM4EKMT2A | |
| SCHEMBL3223692 | 0.80 | ALDH1A1 (0.50) | MTNR1AMTNR1BHSD17B10KDM4EKMT2A | |
| SCHEMBL29957489 | 0.80 | SIRT1 (0.46) | MTNR1AMTNR1BHSD17B10KDM4EKMT2A | |
| SCHEMBL10939480 | 0.77 | KDM4E (0.57) | HSD17B10KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL15331776 | 0.77 | KDM4E (0.42) | MTNR1AMTNR1BKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |