Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | MAPKAPK2 | P49137 | 8/20 | 0.50 |
| ▸ | MAPKAPK5 | Q8IW41 | 3/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1429356 | 1.00 | MTNR1A (0.55) | MTNR1AMTNR1BMAPKAPK2MAPKAPK5SIRT1 | |
| SCHEMBL1428728 | 0.99 | MTNR1A (0.54) | MTNR1AMTNR1BMAPKAPK2MAPKAPK5SIRT1 | |
| SCHEMBL1428978 | 0.97 | MTNR1A (0.52) | MTNR1AMTNR1BMAPKAPK2MAPKAPK5SIRT1 | |
| SCHEMBL29957756 | 0.93 | ALDH1A1 (0.50) | MTNR1AMTNR1BMAPKAPK2MAPKAPK5SIRT1 | |
| SCHEMBL3223692 | 0.93 | ALDH1A1 (0.50) | MTNR1AMTNR1BMAPKAPK2MAPKAPK5SIRT1 | |
| SCHEMBL29952409 | 0.86 | MTNR1A (0.45) | MTNR1AMTNR1BMAPKAPK2MAPKAPK5ALDH1A1 | |
| SCHEMBL29957489 | 0.83 | SIRT1 (0.46) | MTNR1AMTNR1BSIRT1ALDH1A1MAPT | |
| SCHEMBL15331776 | 0.80 | KDM4E (0.42) | MTNR1AMTNR1BMAPTKDM4EMEN1 | |
| SCHEMBL29953259 | 0.80 | KDM4E (0.48) | MTNR1AMTNR1BMAPKAPK2ALDH1A1MAPT | |
| SCHEMBL15332675 | 0.80 | KIF11 (0.41) | MTNR1AMTNR1BMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |