SCHEMBL29952483

SCHEMBL29952483

OB(O)c1nccc2occc12

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.40
FADS1 O60427 1/20 0.36
TRPA1 O75762 1/20 0.36
CNR2 P34972 1/20 0.34
DRD1 P21728 4/20 0.33
MAOA P21397 2/20 0.31
MAOB P27338 2/20 0.31
FTO Q9C0B1 1/20 0.31
NFKB1 P19838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11625851 0.72 HTR2C (0.43) HTR2CFADS1TRPA1CNR2DRD1
SCHEMBL2757287 0.68 HTR2C (0.47) HTR2CFADS1TRPA1CNR2DRD1
SCHEMBL22729154 0.68 HTR2C (0.43) HTR2CFADS1TRPA1CNR2DRD1
SCHEMBL557772 0.68 NOS3 (0.43) HTR2CFADS1TRPA1CNR2DRD1
SCHEMBL16488517 0.68 HTR2C (0.43) HTR2CFADS1TRPA1CNR2DRD1
SCHEMBL15688333 0.68 HTR2C (0.43) HTR2CFADS1TRPA1CNR2DRD1
SCHEMBL127374 0.68 FADS1 (0.46) HTR2CFADS1TRPA1CNR2DRD1
SCHEMBL22323315 0.68 TRPA1 (0.46) HTR2CFADS1TRPA1CNR2DRD1
SCHEMBL29615409 0.68 FADS1 (0.46) HTR2CFADS1TRPA1CNR2DRD1
SCHEMBL31426315 0.68 PDE3B (0.42) HTR2CFADS1TRPA1CNR2DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed