Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 8/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 8/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330869 | 0.77 | DDT (0.49) | MKNK2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL16826222 | 0.76 | CYP2A6 (0.50) | MKNK1MKNK2GABRPGABRDGABRA1 | |
| SCHEMBL16835900 | 0.76 | TDO2 (0.47) | MKNK1MKNK2MEN1ALDH1A1DYRK1A | |
| SCHEMBL29952599 | 0.76 | ERN1 (0.52) | MKNK1MKNK2CHEK2MEN1ALDH1A1 | |
| SCHEMBL28439295 | 0.75 | KMO (0.64) | KMOMKNK1MKNK2KDM4EDHODH | |
| SCHEMBL2562012 | 0.75 | GABRP (0.51) | MKNK1MKNK2GABRPGABRDGABRA1 | |
| SCHEMBL2553423 | 0.75 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7019233 | 0.74 | GABRP (0.54) | MKNK1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL16277788 | 0.74 | LMNA (0.56) | KMOMKNK1MKNK2KDM4EDHODH | |
| SCHEMBL13522906 | 0.74 | MKNK1 (0.60) | KMOMKNK1MKNK2KDM4EDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105354-A | Fibroblast activation protein inhibitor | 普拉西斯生物技术有限责任公司 | 2020-12-18 | — | — | CN | disclosed |