Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 4/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954948 | 0.82 | MEN1 (0.52) | MEN1KMT2AALDH1A1TDP1GPR17 | |
| SCHEMBL250205 | 0.79 | ERN1 (0.36) | MEN1KMT2AALDH1A1GPR17PDPK1 | |
| SCHEMBL29955582 | 0.79 | CYP2A6 (0.47) | MEN1KMT2AALDH1A1TDP1GPR17 | |
| SCHEMBL29953709 | 0.71 | CDK1 (0.51) | MEN1KMT2AALDH1A1AHRCDK1 | |
| SCHEMBL1093112 | 0.71 | CDK1 (0.51) | MEN1KMT2AALDH1A1AHRCDK1 | |
| SCHEMBL6902686 | 0.68 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1TDP1CYP2A6 | |
| SCHEMBL953519 | 0.67 | ALDH1A1 (0.70) | MEN1KMT2AALDH1A1TDP1AHR | |
| SCHEMBL248842 | 0.66 | CYP2A6 (0.66) | KMT2AALDH1A1PDPK1CYP2A6MAPT | |
| SCHEMBL29408411 | 0.66 | CYP2A6 (0.66) | KMT2AALDH1A1PDPK1CYP2A6MAPT | |
| SCHEMBL7493525 | 0.66 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1TDP1GPR17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |