Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955582 | 0.82 | CYP2A6 (0.47) | MEN1ALDH1A1KMT2ATDP1DYRK1A | |
| SCHEMBL29952632 | 0.82 | MEN1 (0.39) | MEN1ALDH1A1KMT2ATDP1DYRK1A | |
| SCHEMBL7493525 | 0.82 | ALDH1A1 (0.48) | MEN1ALDH1A1KMT2ATDP1DYRK1A | |
| SCHEMBL7834282 | 0.75 | AHR (0.41) | MEN1ALDH1A1KMT2ATDP1DYRK1A | |
| SCHEMBL31619545 | 0.75 | ERCC5 (0.53) | DYRK1AERCC5FEN1GRIN2DGRIN3B | |
| SCHEMBL6009055 | 0.75 | ERCC5 (0.53) | DYRK1AERCC5FEN1GRIN2DGRIN3B | |
| SCHEMBL8219938 | 0.74 | ERCC5 (0.44) | MEN1ALDH1A1KMT2ATDP1DYRK1A | |
| SCHEMBL10464296 | 0.74 | DYRK1A (0.46) | DYRK1AERCC5FEN1GRIN2DGRIN3B | |
| SCHEMBL7824904 | 0.74 | AHR (0.40) | MEN1ALDH1A1KMT2ATDP1DYRK1A | |
| SCHEMBL1093112 | 0.73 | CDK1 (0.51) | MEN1ALDH1A1KMT2AAHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |