Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015826 | 0.84 | RAD52 (0.35) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL27767002 | 0.71 | KDM4E (0.47) | ALDH1A1KDM4EHSD17B10CYP3A4MAPT | |
| SCHEMBL9225445 | 0.69 | GPR84 (0.33) | — | |
| SCHEMBL7613712 | 0.69 | CHEK1 (0.37) | — | |
| SCHEMBL442438 | 0.69 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10CYP3A4CYP1A2 | |
| SCHEMBL10376665 | 0.68 | LMNA (0.44) | ALDH1A1KDM4EHSD17B10LMNAMAPT | |
| SCHEMBL5255523 | 0.68 | ALDH1A1 (0.65) | ALDH1A1KDM4EHSD17B10CYP3A4CYP1A2 | |
| SCHEMBL3293016 | 0.67 | ALDH1A1 (0.52) | ALDH1A1KDM4EHSD17B10CYP3A4CYP1A2 | |
| SCHEMBL132741 | 0.67 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10CYP3A4CYP1A2 | |
| SCHEMBL27788591 | 0.67 | KDM4E (0.46) | ALDH1A1KDM4EHSD17B10CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |