Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955583 | 0.86 | MGLL (0.49) | MGLLKIF11TRPV6ORAI1ORAI2 | |
| SCHEMBL4727635 | 0.77 | CTDSP1 (0.53) | MGLLPTPRCTRPV1KIF11CES2 | |
| SCHEMBL23206122 | 0.77 | CYP1A2 (0.57) | PTPRCTRPV1KIF11TSHRMAPK1 | |
| SCHEMBL16061157 | 0.77 | CYP1A2 (0.43) | TRPV1CES2ACHE | |
| SCHEMBL29956515 | 0.76 | TRPV1 (0.43) | TRPV1KIF11 | |
| SCHEMBL3200547 | 0.74 | CYP1A2 (0.59) | ACHE | |
| SCHEMBL29951724 | 0.74 | CYP1A2 (0.59) | ACHE | |
| SCHEMBL24807944 | 0.74 | CYP2A6 (0.45) | TRPV1TSHR | |
| SCHEMBL28477357 | 0.74 | MCL1 (0.55) | TRPV1 | |
| SCHEMBL10408737 | 0.74 | ALDH1A1 (0.56) | PTPRCKIF11CNR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |