Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8222699 | 0.85 | HSD17B1 (0.58) | CYP1A2HSD17B1HSD17B2KDM4EMEN1 | |
| SCHEMBL10594812 | 0.82 | CTDSP1 (0.44) | CTDSP1CYP1A2TRPV1HSD17B1HSD17B2 | |
| SCHEMBL2054647 | 0.81 | CTDSP1 (0.53) | CTDSP1CYP1A2HSD17B2MEN1GAA | |
| SCHEMBL10408737 | 0.78 | ALDH1A1 (0.56) | CYP1A2PTPRCMAPTHPGDKIF11 | |
| SCHEMBL23206122 | 0.77 | CYP1A2 (0.57) | CYP1A2TRPV1PTPRCMEN1GAA | |
| SCHEMBL4078183 | 0.77 | F2 (0.49) | TRPV1PTPRCKDM4EMEN1GAA | |
| SCHEMBL18243149 | 0.77 | PTPRC (0.44) | CYP1A2TRPV1PTPRCKDM4EKIF11 | |
| SCHEMBL29952666 | 0.77 | MGLL (0.49) | TRPV1PTPRCKIF11CES2MGLL | |
| SCHEMBL13554525 | 0.75 | CTDSP1 (0.47) | CTDSP1CYP1A2TRPV1HSD17B1HSD17B2 | |
| SCHEMBL12310592 | 0.74 | KIF11 (0.44) | KDM4EMAPTKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020306-A2 | ISOINDOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008020306-A2 | ISOINDOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2008-02-21 | — | — | WO | disclosed |